Balsalazide Disodium vs. Mesalamine in Mildly to Moderately Active Ulcerative Colitis. Bausch Health logo. Bausch Health. Status and phase.
Mesalamine is known to be substantially excreted by the kidney, and the risk of adverse reactions to balsalazide disodium, which is converted to mesalamine, may be greater in patients with impaired renal function.
Although no information exists on the excretion of balsalazide into breastmilk, it is metabolized to the active drug mesalamine. vs. non-covalent
Chemical Structure of 5-Aminosalicylate (Mesalamine) and Its Pro-Drugs: Sulfasalazine, Balsalazide, and Olsalazine Oral vs Topical Mesalamine for Maintenance
Balsalazide is a novel mesalamine prodrug, activated by colonic bacteria. The aim of this study was to compare the efficacy and safety of balsalazide with that of a pH-dependent formulation of mesalamine in active UC. Methods: A randomized, double-blind study was per-formed comparing balsalazide, 6.75 g daily, with me-
Summary: We compare the side effects and drug effectiveness of Balsalazide disodium and Mesalamine. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 86,735 people who take Balsalazide disodium and Mesalamine, and is updated regularly.
Compare Balsalazide vs Mesalamine head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
Balsalazide 750 mg (Colazal; generics). Olsalazine (Dipentum). Mesalamine delayed release tabs (Delzicol). Mesalamine capsules (Apriso).
balsalazide, mesalamine, olsalazine and sulfasalazine. Balsalazide, mesalamine and olsalazine were developed to maintaining the overall therapeutic benefit of sulfasalazine while improving tolerability.4-17 Upon oral administration mesalamine is absorbed in the small intestine and does not reach the colon.
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