Allopurinol renal dosing

Renal-dosing of allopurinol compounds the poor management of gout and adds to the perception that allopurinol may be detrimental for renal

4 Allopurinol dose needs to be adjusted in renal failure. Maximum daily dose of allopurinol is 800 mg/day. Dose adjustments may be necessary if allopurinol

Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted

Allopurinol in renal impairment. In patients with renal impairment,c use a lower starting dose of allopurinol.17 The maximum maintenance dose

Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted

Table 1. Suggested Dosing of Allopurinol . Treatment should be initiated on a dose of allopurinol adjusted according to renal function. Then the dose of

Table 1. Suggested Dosing of Allopurinol . Treatment should be initiated on a dose of allopurinol adjusted according to renal function. Then the dose of

Renal failure is rarely associated with hypersensitivity reactions to allopurinol. Patients with decreased renal function do require lower doses of allopurinol.

Alternatively, colchicine Lowering the starting dose of allopurinol appropriate to the level of renal function reduces the risk of allopurinol.