Plavix and omeprazole interaction

☑️@plavix_and_omeprazol · 8541 subscribers · Content 18+ 🔞
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Actual: While we appear to not fully understand the complete mechanism behind the interaction, numerous studies have shown that taking Plavix and omeprazole together reduces the effectiveness of Plavix. In other words, omeprazole can reduce the antiplatelet effect of Plavix and increase the risk for cardiovascular events.
4.6 rating 2025-04-24
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Avoid concomitant use of Plavix with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of Plavix [see Drug Interactions (

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Clopidogrel (marketed as Plavix) and Omeprazole. (marketed as Prilosec) – Drug Interaction. Available at MedWatch/SafetyInformation/

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Avoid concomitant use of Plavix with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of Plavix [see Drug Interactions (

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Plavix) to Alert Healthcare Professionals about a Drug Interaction with Omeprazole (Marketed as Prilosec FDA Reminder to Avoid Concomitant Use of Plavix (

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Plavix (clopidogrel) patients should be Leading cardiologists challenge clinical importance of interaction between clopidogrel (Plavix) and omeprazole

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A Major Drug Interaction exists between omeprazole and Plavix. View detailed information regarding this drug interaction.

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Plavix Interactions: Alcohol, Medications, and Others. omeprazole (Prilosec) esomeprazole (Nexium) can decrease the effectiveness of Plavix: CYP2C19 inducers rifampin (Rimactane)

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Drug interactions are reported among people who take Omeprazole and Plavix. Common interactions include dizziness among females and chronic kidney disease among males. The phase IV clinical study analyzes what interactions people have when they take Omeprazole and Plavix.

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Avoid concomitant use of Plavix with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of Plavix [see Drug Interactions (

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