Grapefruit juice can decrease blood levels of levothyroxine, potentially decreasing the effectiveness of levothyroxine. Clinical research shows that grapefruit juice modestly decreases levothyroxine levels by 11% by inhibiting organic anion transporting polypeptide (OATP). Grapefruit juice is thought to affect OATP for only a short time.
Grapefruit juice may slightly delay the absorption of levothyroxine, but it seems to have only a minor effect on its bioavailability. Accordingly, the clinical relevance of the grapefruit juice-levothyroxine interaction is likely to be small. Introduction Grapefruit juice increases the plasma concentrations of
Synthroid and levothyroxine both contain the active drug levothyroxine. Synthroid and grapefruit. Grapefruit and grapefruit juice may both interact
Grapefruit juice can decrease blood levels of levothyroxine, potentially decreasing the effectiveness of levothyroxine. Clinical research shows that grapefruit juice modestly decreases levothyroxine levels by 11% by inhibiting organic anion transporting polypeptide (OATP). Grapefruit juice is thought to affect OATP for only a short time.
Grapefruit juice can decrease blood levels of levothyroxine, potentially decreasing the effectiveness of levothyroxine. Clinical research shows that grapefruit juice modestly decreases levothyroxine levels by 11% by inhibiting organic anion transporting polypeptide (OATP). Grapefruit juice is thought to affect OATP for only a short time.
Grapefruit juice can decrease blood levels of levothyroxine, potentially decreasing the effectiveness of levothyroxine. Clinical research shows that grapefruit juice modestly decreases levothyroxine levels by 11% by inhibiting organic anion transporting polypeptide (OATP). Grapefruit juice is thought to affect OATP for only a short time.
Grapefruit juice may cause your body to absorb less levothyroxine Grapefruit juice may delay the absorption of levothyroxine and reduce its
2024. TLDR. Grapefruit juice may slightly delay the absorption of levothyroxine grapefruit juice-levothyroxines interaction is likely to be small. Expand.
The effect of grapefruit on levothyroxine is the opposite: Drinking grapefruit juice or orange juice can inhibit uptake transporters and reduce the drug s absorption.
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