Step 1. Refer to the equianalgesic table to determine that oral morphine 30 mg every 12 hours equals oral morphine 60 mg every 24 hours; oxycodone 20 mg is equivalent to oral morphine 30 mg; and therefore the equianalgesic dose for the patient s oral morphine 60 mg every 24 hours is equivalent to oxycodone 40 mg every 24 hours.
For example, if a patient is receiving 30 mg of sustained-release morphine (MS-Contin) every 12 hours, the breakthrough morphine dosage would be 10 mg administered every 4 hours.
Refer to pediatric IV morphine dosing: Morphine - PO ~30 minutes: 3-5 hours: mg every 4 hours as needed: 6 months: 0.08 to 0.1mg/kg every 3 to 4 hours;
Morphine - IM: minutes: 4-5 hours: 5-10 mg every 4 hours as needed: Refer to pediatric IV morphine dosing: Morphine - PO ~30 minutes: 3-5 hours: mg every
Refer to pediatric IV morphine dosing: Morphine - PO ~30 minutes: 3-5 hours: mg every 4 hours as needed: 6 months: 0.08 to 0.1mg/kg every 3 to 4 hours;
Morphine - IM: minutes: 4-5 hours: 5-10 mg every 4 hours as needed: Refer to pediatric IV morphine dosing: Morphine - PO ~30 minutes: 3-5 hours: mg every
Refer to pediatric IV morphine dosing: Morphine - PO ~30 minutes: 3-5 hours: mg every 4 hours as needed: 6 months: 0.08 to 0.1mg/kg every 3 to 4 hours;
Morphine - IM: minutes: 4-5 hours: 5-10 mg every 4 hours as needed: Refer to pediatric IV morphine dosing: Morphine - PO ~30 minutes: 3-5 hours: mg every 4 hours as needed: 6 months: 0.08 to 0.1mg/kg every 3 to 4 hours; 6 months and 50kg: 0.2 to 0.5mg/kg every 3 to 4 hours; 6 months and 50kg: 15 to 20mg every 3 to 4 hours
buprenorphine or morphine treatment arm. After randomization infants will receive a syringe with either morphine or placebo every 4 hours and every 8 hours
Regards, Jack