Hydroxybupropion

Hydroxybupropion (code name BW 306U), or 6-hydroxybupropion, is the major active metabolite of the antidepressant and smoking cessation drug bupropion.

Hydroxybupropion (code name BW 306U), or 6-hydroxybupropion, is the major active metabolite of the antidepressant and smoking cessation drug bupropion.

Radafaxine ; (S,S)-Hydroxybupropion; (2S,3S)-Hydroxybupropion; GW-353,162 Oral none.

Bupropion is metabolized in the body by a variety of pathways. The oxidative pathways are by cytochrome P450 isoenzymes CYP2B6 leading to R,R - and S,S -hydroxybupropion and, to a lesser degree, CYP2C19 leading to 4'-hydroxybupropion.

Bestel de Hydroxybupropion D8 bij Chiralix.

The elimination half-life of hydroxybupropion is approximately 20 ( 5) hours, and its AUC at steady state is about 13 times that of bupropion. The times to peak concentrations for the erythrohydrobupropion and threohydrobupropion metabolites are similar to that of hydroxybupropion.

However, although applied over a period of 2 weeks, serum concentrations of bupropion and hydroxybupropion remained low without sufficient response (bupropion: 15.8 ng/mL, hydroxybupropion: 505 ng

by AR Masters 2024 Cited by 31hydroxybupropion, and erythro- and threo-dihydrobupropion. Liquid-liquid 2R,3R-4-hydroxybupropion and 2S,3S-4-hydroxybupropion, respectively. Intra

S-Hydroxybupropion Description Not Available Structure. 3D. Download . MOL SDF 3D-SDF PDB SMILES InChI. Similar Structures. Structure for S-Hydroxybupropion