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Author: Admin | 2025-04-28
Does not cause a significant change in heart rate. Tadalafil does not cause changes in color recognition (blue / green), which is explained by its low affinity for PDEb. In addition, there is no effect of tadalafil on visual acuity, electroretinogram, intraocular pressure and pupil size. In the study of tadalafil in men in a daily dose of 10 mg, no clinically significant effect of the drug on the number and concentration of sperm, motility and morphology of sperm was revealed. Pharmacokinetic propertiesSuctionAfter oral administration, tadalafil is rapidly absorbed. The average maximum concentration (Cmax) in plasma is reached on average 2 hours after ingestion. The speed and degree of absorption of tadalafil do not depend on food intake, therefore the drug CIALIS can be taken regardless of food intake. Dosing time (morning or evening) did not have a clinically significant effect on the rate and extent of absorption. The pharmacokinetics of tadalafil in healthy individuals is linear with respect to time and dose. In the dose range of 2.5 to 20 mg, the area under the concentration-time curve (AUC) increases in proportion to the dose. Equilibrium plasma concentrations are achieved within 5 days when the drug is taken once a day. The pharmacokinetics of tadalafil in patients with erectile dysfunction is similar to the pharmacokinetics of the drug in persons without erectile dysfunction. Add this long-acting drug to your cart for the joy of sex and urination.
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