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Author: Admin | 2025-04-28
Of liquid tasimelteon and patients aged 16 years and older received 20 mg capsules once a day. Patients or their guardians recorded the patients’ total nighttime sleep and sleep quality. Tasimelteon’s effectiveness was determined based on the 50% of nights with the worst sleep quality and the 50% of nights with the least nighttime sleep in each 4-week period.When patients took tasimelteon, they experienced a statistically significant improvement in the 50% worst nights’ sleep quality compared with when they took placebo.Asenapine Patch Now Available for SchizophreniaAsenapine transdermal (Secuado) is now available for the treatment of schizophrenia in adults, Noven Pharmaceuticals Inc. announced in December. The FDA approved asenapine transdermal in October 2019.In a phase 3 study, 616 adults who were experiencing an acute exacerbation of schizophrenia were randomized to asenapine transdermal 7.6 mg/24h or 3.8 mg/24h or placebo. At six weeks, those who used the asenapine patch had significant improvement in their Positive and Negative Syndrome Scale (PANSS) total score compared with those who used a placebo patch. Patients who used the asenapine patch also experienced statistically significant improvement in Clinical Global Impression-Severity scores compared with those who used a placebo patch. ■Metrics & CitationsMetricsCitations Export Citations If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.For more information or tips please see 'Downloading to a citation manager' in the Help menu.View OptionsView options Not a subscriber?Subscribe Now / Learn MorePsychiatryOnline subscription options offer access to the DSM-5-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).FiguresTablesMediaOpen in viewerGo toGo toShow all referencesRequest permissionsExpand AllCollapseExpand TableAuthors Info & Affiliations
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