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Author: Admin | 2025-04-28
A resource to help answer common questions about Advil® DUAL ACTION. Help further uncover the most frequently asked questions about ibuprofen. Patients are often concerned with many aspects of taking new medication in order to deal with their pain. Advil® DUAL ACTION can provide them powerful pain relief, while you provide them ease of mind. Understanding what makes Advil® DUAL ACTION different from regular Advil® can help you identify which treatment is most effective for your patient’s pain. In Advil Dual Action the combination of two active ingredients – ibuprofen and acetaminophen work to fight the pain at its physical core while also signaling to the central nervous system. Understanding how to treat pain, begins with understanding how to communicate with the patient. The following questions and answers will provide a consumer friendly way of addressing all your patients' concerns. Download our Advil® DUAL ACTION FAQ PDF for your office! DOWNLOAD NOW What is Advil® DUAL ACTION and how is it different from regular Advil®? Advil® DUAL ACTION is a combination of ibuprofen (125 mg) and acetaminophen (250 mg)—two distinct mechanisms of action (MOA) working together to fight pain. Regular Advil® features ibuprofen (200 mg) as a stand-alone painkiller. How does Advil® DUAL ACTION work? Advil® DUAL ACTION combines the pain-fighting power of its two active ingredients—ibuprofen and acetaminophen. Ibuprofen, a traditional NSAID, decreases the synthesis of pain- and inflammation promoting prostaglandins via nonselective inhibition of COX-1 and COX-2. Acetaminophen, a non-NSAID analgesic, is believed to exert its effects via central nervous system COX inhibition and activation of central serotonergic pathways.1,2 How does Advil® DUAL ACTION compare to each ingredient used as monotherapy? In a clinical study, Advil® DUAL ACTION provided powerful pain fighting across primary and secondary end points than either ibuprofen 250 mg or acetaminophen 650 mg alone.3 Advil® DUAL ACTION had a fast onset of action3 Advil® DUAL ACTION had an 8-hour duration of action3 Are there any new side effects or safety concerns with Advil® DUAL ACTION? Advil® DUAL ACTION combines two of the most widely used analgesics in the world, both with established efficacy and
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