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Author: Admin | 2025-04-28
The Internet. For information regarding typical use outside of a medical or research setting, various online resources were queried for experience reports, including Erowid (Erowid.org), Bluelight (bluelight.org), Drugs-Forum (Drugs-Forum.com), and psychonautWiki (psychonautwiki.org). The following data were extracted from each experience report: motivations for use; side effects noted, with special attention paid to the incidence of extrapyramidal symptoms; dose reported; how the drug was obtained; and any drugs that were co-ingested with adrafinil. The limitations of these data include reporting bias; lack of placebo controls; lack of methods to verify the dose, purity, or identity of the consumed substance; and user reports potentially arising from a biased sample of users (i.e., those who frequent online drug forums).A total of 49 experience reports were obtained for analysis, including 43 reports (88%) from Erowid, five (10%) from Drugs-Forum, and one (2%) from psychonautWiki, as of September 29, 2020. Although adrafinil was mentioned several times on Bluelight.org, there were no discrete experience reports available for analysis.Of the 49 experience reports obtained, 44 (90%) reported the dose ingested. The dose ingested ranged from 50 mg to 2,700 mg, with a median dose of 600 mg and mean dose of 623 mg (SD=438 mg). The source of adrafinil was referenced in 19 (38%) reports (Table 1). Of these, 18 (95%) reported obtaining adrafinil from an online vendor, while one (5%) procured adrafinil from a friend who had purchased it from an online vendor. Adrafinil is available online through websites such as nootropicsdepot.com, purenootropics.net, zachattacksupplements.com, and newmind.com, at prices ranging from $1.87 to $4.18 per gram. No alternative names for adrafinil were identified. Each website categorized adrafinil as a "nootropic" chemical or compound.TABLE 1. Summary of experience reports of motivation, side effects, and source of adrafinilaReportN%Motivation for use (N=46) Focus, productivity, or motivation2759 Wakefulness1635 Substitute for another
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