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Author: Admin | 2025-04-28
To PERJETA's market dominance[3].Future ProspectsDespite the challenges, PERJETA remains a critical component of Roche’s HER2 franchise. The company has raised its full-year guidance for 2024, expecting mid-single-digit revenue growth and high-single-digit core EPS growth, partly driven by the performance of its HER2 franchise, including PERJETA[1].Global Market ExpansionThere are prospects to enhance PERJETA's accessibility in international markets, broadening its patient base. However, this will depend on navigating regulatory challenges and competition from emerging treatments[2].Technological AdvancementsThe development of novel anticancer drug delivery technologies, such as the ENHANZE technology by Halozyme Therapeutics, could further boost the market for PERJETA by improving the ease and efficiency of drug administration[4].Key TakeawaysRobust Revenue Growth: PERJETA has consistently shown strong revenue growth, with $4.42 billion in sales in 2022.Market Challenges: Faces competition from PHESGO, ENHERTU, and upcoming biosimilars.Regulatory and Technological Factors: Patent expiration and advancements in drug delivery technologies will shape its future.Global Expansion: Prospects for increasing accessibility in international markets.FAQsWhat is PERJETA used for?PERJETA (pertuzumab) is used for the treatment of HER2-positive metastatic breast cancer, neoadjuvant HER2-positive breast cancer, and adjuvant HER2-positive breast cancer[2].How does PERJETA work?PERJETA acts as an HER2 inhibitor, targeting a different region of the HER2 receptor compared to HERCEPTIN, allowing for a combination therapy that enhances treatment efficacy[2].What are the main challenges facing PERJETA in the market?PERJETA faces challenges from competition by other treatments like PHESGO and ENHERTU, the threat of biosimilars with its patent expiration, and regulatory challenges[1][3].How has the introduction of PHESGO impacted PERJETA's sales?The introduction of PHESGO has led to a cannibalization of some of PERJETA's market share, particularly in the EU, but has also contributed to the overall growth of Roche’s HER2 franchise[1].What are the future prospects for PERJETA?Despite challenges, PERJETA remains a key component of Roche’s HER2 franchise, with prospects for global market expansion and technological advancements in drug delivery[1][4].SourcesRoche's HER2-Positive Breast Cancer Treatment Franchise - DelveInsightTop Performing Drug – Perjeta (January Edition) - PharmaShotsBiologics Market Report 2024-2034 - VisiongainPertuzumab Market Size, Trends And Forecast To 2028 - Coherent Market InsightsGlobal revenue Perjeta 2018-2022 - Statista
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