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Author: Admin | 2025-04-28
Risk of falls.Subutex could cause constipation, laxatives may have been required by some people.Subutex had been associated with androgen deficiency which can cause symptoms such as low libido, impotence, erectile dysfunction, amenorrhea, or infertility. Talk to your doctor if this happens to you.If Subutex was administered with other drugs that also released serotonin, such as tramadol, lithium, or antidepressants, a condition called serotonin syndrome could develop. Symptoms of serotonin include agitation or restlessness, sweating, diarrhea, headache, confusion, rapid heart rate, high blood pressure, dilated pupils, loss of muscle coordination, twitching muscles, or muscle rigidity.Women of childbearing age were instructed to use adequate contraception to ensure they did not become pregnant while being administered Subutex, because of the risk of the baby being born with neonatal withdrawal syndrome. Breastfeeding was not recommended while being administered Subutex.Subutex could impair your ability to drive or operate machinery unless you were tolerant of its effects. Subutex was a schedule III product. 6. Response and effectiveness Sublingual preparations of buprenorphine vary in the time they take to dissolve (from just a few minutes to up to 12 minutes). People should not eat, drink, or talk during this time. Some relief from withdrawal symptoms should be expected within 30 minutes of the first dose. It may take several doses before the full effects are seen. A decrease in the response to buprenorphine may indicate that a higher dosage is needed. 7. Interactions Medicines that interacted with Subutex either decreased its effect, affect how long it worked, increased side effects, or had less of an effect when taken with Subutex. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Common medications that interacted with Subutex included:antidepressants, such as tricyclic antidepressants (eg, amitriptyline), monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine), or SSRIs (eg, fluoxetine, sertraline)antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) and atypical antipsychotics (eg, olanzapine, quetiapine, ziprasidone)any medication that inhibits or induces CYP3A4any medication that may cause drowsiness, such as amphetamines, benzodiazepines (eg, diazepam, lorazepam), first-generation antihistamines (such as doxylamine or promethazine), metoclopramide, or opioids (such as codeine, methadone, or morphine)HIV medications such as ritonavirnaloxone and naltrexoneQT-prolonging medications such as amiodarone and flecainiderifampinSt. John's Wort.Alcohol or illegal or recreational drugs were not recommended with Subutex.Note that this list is not all-inclusive and
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